Global Substance Registration System - GSRS

The primary goal of the Global Substance Registration System (GSRS) program is the production of software to assist agencies in registering and documenting information about substances found in medicines and other regulated products. GSRS provides common identifiers including FDA UNIIs for all substances used in regulated products. It utilizes definitions of substances globally-consistent with ISO 11238 and DTS 19844 including active substances under clinical investigation.

Many organizations contribute to the GSRS project including the Food and Drug Administration (FDA) and the National Center for Advancing Translational Science (NCATS). For more information about GSRS, code and public data, please consult https://gsrs.ncats.nih.gov/.